Applications

Single-stranded DNA expands opportunities in genetic medicines and beyond

Gene Editing

Single-stranded DNA technology serves as an optimal donor template for homology-directed repair (HDR)-mediated gene knock-ins, offering higher knock-in efficiency while minimizing cytotoxicity. This approach is particularly beneficial for primary cells, such as T-cells, which exhibit high sensitivity to double-stranded DNA and achieve superior editing outcomes with ssDNA.

Transient Expression

Single-stranded DNA as transient gene expression vector or vaccine combines mRNA's safety with dsDNA's stability and cost-effectiveness.

Diagnostics

Revolutionize in vitro diagnostics with GXstrands' scalable long-chain ssDNA, enabling precise detection, robust signal amplification, and efficient assay development for advanced medical applications.

Other Applications

GXstrands supports customers across a wide range of fields, focusing on the manufacture of high-quality custom ssDNA at scale to drive groundbreaking technologies. Our future product offerings will include ssDNA solutions for in vitro transcription and AAV manufacturing.